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KMID : 0376119920190010013
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Medical Journal of the Red Cross Hospital
1992 Volume.19 No. 1 p.13 ~ p.18
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Clinical Trial with Intraperitoneal Hyperthermic Perfusion for Intraabdominal Cancer with Peritoneal Metastasis
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Abstract
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Intraperitoneal hyperthermic perfusion(IPHP) and chemotherapy has been tried after surgical treatment for 8 patients with advanced intraabdominal cancer in Seoul Red Cross Hospital from early in 1990. There were two patients with peritoneal
recurrence
and metastasis, who have been in good health for a long time after IPHP combined with surgery.
Two 86-year-old and 65-year-old women were treated for recurrent colon cancer and cystadenocarcinoma by surgery and by thermal infusion and chemotherapy with a machine designed specifically for the treatment of cancers of serosal surface. After
completion of surgery, the patients peritoneal cavity was instilled with 3 liters of 5% lactated Ringers solution. They were then attached to hyperthermic perfusion system which elevated the temperature by warming to 44℃and recirculated the
effusion
solution with mitomycin(10 microgramer ml).
The patients postoperative courses were uneventful except for Pneumonia & exacervation of athmatic attack in the case of cystadenocarcinoma. These results show that IPHP using mitomycin(MMC) combined with surgery is a safe, reliable treatment for
patients with peritoneal implantation of intraabdominalcancers.
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KEYWORD
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